Research Technician III

Job Posting # 876557

Position: Research Technician III
Site: Princess Margaret Cancer Centre
Department: Living Biobank
Reports to: Principal Investigator
Pay Scale: $60,904 – $76,131 per annum (Commensurate with experience and consistent with UHN Compensation Policy)
Hours: 35 hours per week
Status: Permanent Full-time

University Health Network (UHN) is looking for an experienced professional to fill the key role of Research Technician III in our Living Biobank Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN’s five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

The Living Biobank at the Princess Margaret Cancer Centre is a collaborative between PM Researchers and UHN Biospecimen Core to establish a central repository and provide services for the use of patient-Derived tumor organoid (PDO) and Xenograft (PDX) models.

The applicant will be responsible for growing and characterization of organoid cultures derived from cancer patient tissues at the Princess Margaret Cancer Centre Living Biobank Facility.


  • At minimum, a B.Sc. in Biological Sciences or related field, and or M.Sc. preferred
  • At minimum, six (6) years of experience in biomedical laboratory research required
  • Strong background and working experience in molecular biology, biochemistry and microscopy techniques is required
  • Over five (5) years of experience in 2D cell culture, 3D culturing methods or stem cell research methodologies is expected
  • Knowledge in bioinformatics and animal work is an asset
  • Excellent problem recognition and problem solving abilities
  • Effective organizational, time management and prioritization skills
  • Strong communication skills and ability to present scientific findings
  • Self-starter able to work independently and as part of a team

Key Duties:

The applicant will develop and characterize organoid cultures from primary patient tissue in the Princess Margaret Living Biobank Facility.

  • Initiating organoid cultures using already established protocols
  • Developing novel organoid culturing methods
  • Conducting data analysis and preparing scientific reports
  • Presenting research to other members of the research team
  • Preparing samples for histology analysis
  • Preparing samples for genomic analysis
  • Performing mycoplasma testing of organoid/cell cultures
  • Performing growth analysis and drug screening of organoid/cell cultures
  • Performing animal work

The applicant may also be expected to participate in data analysis including bioinformatics and biostatistics. At all times, the individual is expected to support the overall mission of the facility.
If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume and covering letter. You will also be required to complete some initial screening questions.

Posted Date: May 6, 2021 Closing Date: May 20, 2021

For current UHN employees, only those who have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN’s attendance management program, and possess all the required experience and qualifications should apply.

University Health Network thanks all applicants, however, only those selected for an interview will be contacted.

UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process providing the applicant has met the Bona-fide requirements for the open position. Applicants need to make their requirements known when contacted

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